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 Affliction Combat 
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For Warlocks who specialize in Affliction, DoTs and Drains are gonna be the 
major source of spells and damage you'll be using. Affliction fighting takes
more time than Destruction, but it's generally safer, better for grinding, 
less downtime, easier to handle bosses and hard hitting mobs by kiting them,
more or less unlimited mana and so on. Affliction Warlocks do have good damage,
but they rely more on damage over time than nuking. This causes their damage to
be more even, and it builds threat slower than other builds because there's no
instant jump in DPS(A Destruction Warlock might start off with a Shadowbolt 
Crit for 1500, instantly building up alot of threat, whereas Affliction has a
steady but good damage, as long as the DoT's stay in place on the debuff-slots.

A typical fight will often consist of sending in the Voidwalker, to avoid 
getting aggro. Affliction locks almost never gets aggro as long as they send 
in the Walker first, as they rely on slow but steady dps which allows the 
Voidwalker to build threat and hold it during the fight. 

Many Warlocks use the Imp instead for Dark Pact, but since the Imp cannot hold
the aggro, neither survive it, the enemies will always go directly for the
Warlock. Affliction isn't so bad even under direct attack, as Fel Concentration
will help prevent interruption when channeling Drain Life, and Nightfall makes
Shadow Bolt instant.

Once/if the Voidwalker has secured the aggro, then it's time to dot up the
target. An Affliction lock will usually go for either Curse of Agony or Curse
of Shadows, then Corruption and Immolation and Siphon Life. With all those 
ticking on the target, Drain Life is a popular skill to use. By the time the
Warlock has started using Drain Life, the target will already be greatly 
damaged, and it's quick and easy to finish it off. Some prefer to even wand the
target if it's low on health as it saves even more mana for the next fight.

If done correctly, the Warlock should be at full or close to full health. 
If the imp is up, then a few Dark Pact should put the Warlock ready for the 
next mob, and this can go on and on without rest. It's a great grinding tactic
as it reduces downtime and saves food/drink costs.

Another strong point to an Affliction Warlock, is their ability to deal with
many mobs at once, much safer and effective than both Demonologist and 
Destructionist Warlocks. With the help of Improved Corruption and Siphon Life,
the amount of instant DoT's go from 1 to 3, making kiting and handling several
targets at once alot easier. They can then be feared around the area while the
dots slowly tick away, and Siphon Life keeps you healed. With Siphon Life on
tree targets at the same time, you'll be healed alot, and with Dark Pact you
can keep your mana up constantly for new fears and dots. 

curse of Exhaustion is also a great tool for any Warlock who specializes in
Affliction. It's not that useful for normal mobs as they will die too soon
anyway, but for bosses, it can be very helpful. Bosses tend to be immune to 
fear, but not to curses. This makes it very easy to kite bosses with an 
improved Curse of Exhaustion, meaning the boss has 30% lower runspeed than you.
Put it up on a boss, then quickly Corruption and Siphon Life, and just kite the
boss around while recasting constantly. With the help of Dark Pact, you won't
run dry of mana and the odds of the boss to hit you is slim at best...as long 
as it doesn't use ranged attack. However, bosses have ranged limits as well, 
and if you get outside the limit they will start running after you.

A popular build, SM/DS is exceptionally useful as it allows for all the 
strengths of the Affliction tree except for Dark Pact, while obtaining one of
the best spells in the Demonology Tree, Demonic Sacrifice. It is at the moment
the only way to receive a flat 25% Shadow Damage increase, but it can also
greatly increase your Health Regeneration. 

Siphon Life, Drain Life and a Demonic Sacrificed Voidwalker. It is a sight to
see and to experience. It can keep you going and going in all situations, from
normal grinding to bosses.